Pain medicine https://painmedicine.org.ua/index.php/pnmdcn <p>"Medicina bolu" is a science-and-practice periodical for medical professionals. The main highlighting issue is pain, but not the only one, because in medicine there are no situations where a phenomenon is strictly isolated. Sign up for a print edition and follow up on the site to keep up with important and useful information.</p> <p>Thematic interests of the journal<br>Fundamental aspects of pain (clinical physiology, pathophysiology, pharmacology).<br>Applied aspects of pain (epidemiology, pain assessment, innovative methods of diagnosis and treatment, clinical pharmacology).<br>Clinical aspects of pain (acute pain, chronic pain, perioperative pain, posthumous pain, neuropathic pain, dysfunctional pain).<br>Clinical and anatomical approach to pain (headache, orofacial pain, neck and back pain, toothache, musculoskeletal pain, myofascial pain, fibromyalgia, visceral pain, pelvic pain, cardialgia, etc.).<br>Interdisciplinary approach to pain (in anesthesiology, in surgery, in pediatrics, neurology, vertebrology, in the clinic of internal diseases, oncology, rheumatology, gerontology, gastroenterology, traumatology and orthopedics, otorhinolaryngology, dentistry, obstetrics, gynecology and urology, in the palliative and hospice medicine).<br>Treatment and rehabilitation of patients suffering from pain (pharmacotherapy, physical rehabilitation, medical rehabilitation, alternative methods of treatment, means of psychological and psychotherapeutic influence, invasive methods of pain relief, organization of pain relief).<br>Separate clinical cases and their clinical examination.</p> en-US <p><a style="background-color: transparent; color: #007ab2; font-family: &amp;quot; noto sans&amp;quot;,arial,helvetica,sans-serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: underline; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img style="border-width: 0px;" src="https://i.creativecommons.org/l/by/4.0/88x31.png" alt="Creative Commons License"></a><br style="background-color: transparent; color: #000000; cursor: text; font-family: &amp;quot; noto sans&amp;quot;,arial,helvetica,sans-serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; outline-color: #2d8ac7; outline-style: solid; outline-width: 2px; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;"><span style="display: inline !important; float: none; background-color: transparent; color: #000000; cursor: text; font-family: 'Noto Sans',Arial,Helvetica,sans-serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;">This work is licensed under a </span><a style="background-color: transparent; color: #007ab2; font-family: &amp;quot; noto sans&amp;quot;,arial,helvetica,sans-serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: underline; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;" href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a></p> editor@painmedicine.org.ua (Oleksandr Marchuk) vlvitkovskyi@gmail.com (Viktor Vitkovskyi) Sun, 05 Jan 2020 00:00:00 +0200 OJS 3.1.2.4 http://blogs.law.harvard.edu/tech/rss 60 To the basics of clinical thinking formalization. Main terms with conceptual meaning https://painmedicine.org.ua/index.php/pnmdcn/article/view/210 <p>Medicine’s condition is one of the most relevant scientific and socio-economic problems of the mankind. Eclecticism, presence of multiple contradictions and compilations are typical at the modern stage of it as of a knowledge system. First of all, this state of medicine is conditioned by the absence of systematic structural and functional organization of the human body in the medical scientific and practical activity. Formation of the systematic thinking on the basis of the knowledge about human body as a system is necessary for the solution of this problem. The system of special meanings forms scientific knowledge that determines the form and corresponding thinking method. Knowledge is a reflection of objective reality in our consciousness, represented in symbols of the formal language matrix.</p> <p><strong>Clinical thinking</strong> – specialized form of the internal speech. Its structural units are corresponding definitions, terms and notions. At the same time they are its tools and methods. Certain group of terms has a conceptual meaning for the formation and development of clinical thinking.</p> Viktor Poberezhnyi, Oleksandr Katilov, Oleksandr Marchuk, Oleh Shvydiuk, Iryna Petrik, Oleksii Lohvinov Copyright (c) 2020 https://creativecommons.org/licenses/by/4.0 https://painmedicine.org.ua/index.php/pnmdcn/article/view/210 Sun, 05 Jan 2020 00:00:00 +0200 Perioperative pain management in elderly patients with а proximal femoral fracture: evidence review https://painmedicine.org.ua/index.php/pnmdcn/article/view/200 <p>The purpose of this article is to compare different methods of analgesia during perioperative period in elderly patients with а proximal&nbsp;femoral&nbsp;fracture. The incidence of hip fracture is high and also rises with the age, for example, In Great Britain, number of patients with a hip fracture will be approximately 100 000 in 2033, and it’s also associated with significant healthcare financing. Nevertheless, effective pain management is a big challenge for clinicians because of considerable problems in geriatric patients, including age, physiological changes in the elderly, preexisting comorbidities, cognitive impairment, high risk of delirium, problems with rehabilitation and probability of an independent life [12].&nbsp;&nbsp; Opioids are still the main option for hip fracture pain management, despite differences in pharmacokinetics and pharmacodynamics in elderly patients, which are correlated with high frequency of side effects. Opioid-related&nbsp;adverse drug events&nbsp;are associated with worse patient outcomes such as morbidity, <em>mortality</em> and length of stay increase. Therefore, peripheral nerve&nbsp;blocks as part of <em>multimodal analgesic</em>&nbsp;technique can provide more effective pain control after&nbsp;<em>hip fracture. </em>Comprehensive literature searches focus on the use of peripheral nerves blocks as preoperative analgesia, as postoperative analgesia or as a supplement to general anesthesia for hip fracture surgery.</p> Anastasiia Romanenko, Iurii Kuchyn , Kateryna Bielka, Igor Tokar Copyright (c) 2020 Anastasiia Romanenko, Iurii Kuchyn , Kateryna Bielka, Igor Tokar https://creativecommons.org/licenses/by/4.0 https://painmedicine.org.ua/index.php/pnmdcn/article/view/200 Sat, 08 Feb 2020 00:00:14 +0200 Itching as the onset of pain (part 1) https://painmedicine.org.ua/index.php/pnmdcn/article/view/212 <p>PAIN is a psychophysiological reaction of an organism that occurs with severe irritation of the sensitive nerve endings embedded in organs and tissues. And also pain is the body’s protective reaction. It is signaling about a discomfort and triggers an appropriate response by the body to eliminate the cause of the pain. Pain is one of the earliest symptoms of some diseases [84].</p> <p>ITCHING – an unpleasant sensation of irritation, heartburn and tingling in any area of the skin caused by various factors (exposure to chemicals, bacteria, parasites). This feeling is often manifested by the urgent need to rub or scratch some areas of the skin (or mucous membrane) [85].</p> <p>When considering the pathogenesis of these concepts, a sufficiently large resemblance to the realization of mechanisms of origin, or a certain identity thereof is revealed. The question naturally arises whether itching is an early manifestation of pain, especially in those groups of diseases that are not characterized by pain.</p> <p>Pathology of the hematopoietic system is not accompanied by a symptom such as pain. But for conditions such as iron overload, iron deficiency or polycythemia, itching is a clear symptom.</p> <p>The unknown etiology of chronic itching of the skin is indicative of histological examination of the skin in order to exclude skin lymphoma. One of the least understood mechanisms of itching is itching associated with malignant solid tumors.</p> <p>What pain that itching is a subjective sensation that can have an acute or chronic course, a clear intensity and a very significant impact on quality of life, especially in the case of comorbidity.</p> <p>In addition, the question arises whether itching is an early manifestation of pain, especially in those groups of diseases that are not characterized by pain. How can a doctor manage itching effectively to prevent complications? To these and other questions, we have attempted to systematize the manifestations of itching in pathologies of organs and systems that are not traditionally accompanied by pain.</p> Valerii Kushnir, Svitlana Dmytrenko, Oleksandr Katilov, Nataliia Kushnir Copyright (c) 2020 https://painmedicine.org.ua/index.php/pnmdcn/article/view/212 Sun, 05 Jan 2020 00:00:00 +0200 Morphology of the pathways of intracellular circulation in the brain https://painmedicine.org.ua/index.php/pnmdcn/article/view/213 <p>The article reflects the current position of the issue of morphologies of the pathways of intercellular circulation in the brain. There are covered main, known at present time, data on the features of the exchange between the spinal fluid and intercellular fluid, the ways of elimination of the intertissued fluid of the brain through the so-called “glymphatic system”, its components: transarterial, transvenous, and transglial ways of intercellular fluid outflow from brain tissue. It also raises the question of the role of glia namely astrocytes and ependymocytes – as the main cells forming the haemato-encephalic barrier and participating in the intercellular circulation.</p> Yurii Kondor, Vitalii Tykholaz, Yurii Huminskyi Copyright (c) 2020 https://painmedicine.org.ua/index.php/pnmdcn/article/view/213 Sun, 05 Jan 2020 00:00:00 +0200