Rationale for preoperative (versus postoperative) administration of meloxicam for acute pain management and assessment of satisfaction in patients with femoroacetabular impingement who underwent hip arthroscopy

Authors

  • Yongqing Li Department of Anesthesiology, Shanghai Liqun Hospital, Putuo District, Shanghai, China
  • Guowei Li Department of Anesthesiology, Wuxi Fifth People’s Hospital Affiliated to Jiangnan University, Wuxi, China
  • Kai Zhang Department of Orthopedics, Shanghai Liqun Hospital, Putuo District, Shanghai, China
  • Menglu Jiang Department of Anesthesiology, Wuxi No.9 People’s Hospital Affiliated to Soochow University, Wuxi, China
  • Xu Dai Department of Anesthesiology, Wuxi No.9 People’s Hospital Affiliated to Soochow University, Wuxi, China
  • Zhenqing Liu Department of Anesthesiology, Wuxi No.9 People’s Hospital Affiliated to Soochow University, Wuxi, China
  • Ou Wang Department of Orthopedics, Shanghai Liqun Hospital, Putuo District, Shanghai, China

DOI:

https://doi.org/10.31636/pmjua.v6i1.3

Keywords:

Meloxicam, femoroacetabular impingement, hip arthroscopy, efficacy, safety

Abstract

Objective: This study is aimed to compare the analgesic effect and safety of preoperative (versus postoperative) meloxicam administration in femoroacetabular impingement (FAI) patients who underwent hip arthroscopy (HA).

Methods: Totally, 136 FAI patients who scheduled for HA were recruited, then they were randomly assigned to preoperative administration (PREA) group (orally meloxicam 7.5 mg in 12h, 24h before operation, then orally 7.5 mg/d from 12h to Day 7 after operation; N=68) or postoperative administration (POSA) group (orally meloxicam 7.5 mg/d from 12h to Day 7 after operation; N=68) in 1:1 ratio. Furthermore, pain visual analog scale (VAS) score, patient satisfaction score, Harris hip score (HHS) and adverse events were assessed. Besides, the accumulated pethidine consumption for rescuing analgesia was calculated.

Results: Acute pain VAS score at rest (Day1 – Day2) and pain VAS score at motion (Day1 – Day3) were decreased, meanwhile short-term patient satisfaction score (Day1–Day3) was increased in PREA group compared with POSA group; however, these scores in long-term period were of no difference between PREA group and POSA group (Day3–Month3). Furthermore, accumulated pethidine consumption on Day3 and Day7 were attenuated in PREA group compared with POSA group. Additionally, HHS at any assessed time points (Day7–Month3) did not differ between two groups. Besides, no difference in the incidence of adverse events was found between two groups.

Conclusions: Preoperative meloxicam administration displays superior efficacy in short-term pain control, patient satisfaction improvement and attenuated consumption of rescue analgesia over postoperative meloxicam administration in FAI patients who underwent HA.

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References

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Rationale for preoperative (versus postoperative)  administration of meloxicam for acute pain management  and assessment of satisfaction in patients with  femoroacetabular impingement who underwent  hip arthroscopy

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Published

2021-04-28

How to Cite

1.
Li Y, Li G, Zhang K, Jiang M, Dai X, Liu Z, Wang O. Rationale for preoperative (versus postoperative) administration of meloxicam for acute pain management and assessment of satisfaction in patients with femoroacetabular impingement who underwent hip arthroscopy. PMJUA [Internet]. 2021 Apr. 28 [cited 2021 Sep. 24];6(1):19-2. Available from: https://painmedicine.org.ua/index.php/pnmdcn/article/view/247

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