Experience in the local use of 0.25% bupivacaine for the treatment of postoperative pain


  • Y N Babina National Pirogov Memorial Medical University, Vinnytsia, Ukraine
  • V S Konoplitsky National Pirogov Memorial Medical University, Vinnytsia, Ukraine
  • O O Kalinchuk National Pirogov Memorial Medical University, Vinnytsia, Ukraine
  • D V Dmytriiev National Pirogov Memorial Medical University, Vinnytsia, Ukraine https://orcid.org/0000-0001-6067-681X
  • O A Nazarchuk National Pirogov Memorial Medical University, Vinnytsia, Ukraine
  • E V Andriets National Pirogov Memorial Medical University, Vinnytsia, Ukraine




local anesthetics, bupivacaine, postoperative pain


According to British scientists, about 300 million operations are performed around the world annually. They cause acute postoperative pain, the management of which is crucial for improving patient outcomes and reducing healthcare costs. Local anesthetic infiltration before closing the surgical incision is a commonly used technique in the operating room. This review focuses on the use of local anesthetic infiltration, 0.25% bupivacaine, into surgical incisions to reduce postoperative pain, as confirmed by an estimate of a reduction in the use of postoperative opioids and a visual analogue scale (VAS). The presented clinical cases and the combined analgesia scheme with infiltration of a local anesthetic into the postoperative wound were used to make it possible to argue about the effectiveness of anesthesia because on the peripheral mechanism of pain. Infiltration analgesia reduced the need for opioids and the time of stay in hospitals. It was concluded that there is a need for further research on methods of delivering anesthetics to postoperative wounds for pain management and improving the quality of treatment.


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Досвід місцевого використання 0,25% бупівакаїну для лікування післяопераційного больового синдрому



How to Cite

Babina YN, Konoplitsky VS, Kalinchuk OO, Dmytriiev DV, Nazarchuk OA, Andriets EV. Experience in the local use of 0.25% bupivacaine for the treatment of postoperative pain. PMJUA [Internet]. 2019Jun.4 [cited 2021May15];4(1):17-23. Available from: https://painmedicine.org.ua/index.php/pnmdcn/article/view/187



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