Submission of the use of the method of preemtive analgesia with acetaminophen for perioperative period in children


  • D V Dmytriiev Vinnytsia National Pirogov Memorial Medical University
  • O V Marchuk Vinnytsia National Pirogov Memorial Medical University
  • V L Vitkovskyi Vinnytsia National Pirogov Memorial Medical University
  • V Yu Kebenko Vinnytsia National Pirogov Memorial Medical University



analgesia, pain, postoperative period, children


In the structure of postoperative anesthesia in children, as well as in other age groups, the main place is occupied by narcotic analgesics; the route of administration is traditional– intramuscular. The purpose of the study was to in-crease the effectiveness of postoperative analgesia with opioid analgesics in children. The study was conducted in 37 children with a mean age of 3.2 ± 0.8 years operated on tumors in the peritoneal space (27 children, 73%), kidney tumors (8chil-dren, 22%) and ovarian tumors (2 children, 5%). Comprehensive study of the reactions of pain behavior, physiological parameters and laboratory stress tests showed that the use of the scheme of analgesia based on acetaminophen 30 mg/kg and the method of continuous infusion of drugs (fentanyl in a dose of 5 μg/kg/h) for postoperative anesthesia leads to effective analgesia after traumatic operations in the neonatal period. The use of the method of continuous intravenous infusion of opioid analgesics leads to a pronounced, to varying degrees, sedation and respiratory depression, which enables children to adapt well to the apparatus of mechanical ventilation after various surgical interventions.


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Submission of the use of the method of preemtive analgesia with acetaminophen for perioperative period in children



How to Cite

Dmytriiev DV, Marchuk OV, Vitkovskyi VL, Kebenko VY. Submission of the use of the method of preemtive analgesia with acetaminophen for perioperative period in children. PMJUA [Internet]. 2019 Feb. 21 [cited 2023 Feb. 8];3(4):65-9. Available from:



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