Experience of Dexmedetomidine using for intraoperative analgosedation during ophthalmic operations

Authors

  • Maxim Khodakovsky National Pirogov Memorial Medical University, Vinnytsia

DOI:

https://doi.org/10.31636/pmjua.v6i3.5

Keywords:

analgosedation, Dexmedetomidine, autonomic nervous system

Abstract

Background. The aim of the study is to evaluate the quality and safety of the sedative effect of anesthesia in ambulant ophthalmic surgery by using continuous intravenous infu­sion of Dexmedetomidine.
Materials and Methods. Patients were randomized into groups by age (people from 65 to 75 years old, old age 76 years, middle age, young people, children), by gender (men, women). The physical status of patients was assessed using the ASA scale and the dynamics of vegetatic activity by the Kerdo index. Sedation was assessed using the Richmond Sedation Scale RASS.
Results. It was found that the difference in the frequency of adverse effects of the appointment of Dexmedetomidine clearly confirms the need to adjust the dose of Dexmede­tomidine, depending on the state of the autonomic nervous system. The use of Dexmedetomidine according to the rec­ommendations made it possible to achieve a safe level of sedation and eliminate side effects in ambulant ophthalmic surgery.
Conclusions:

  1. Parenteral continuous infusion of Dexmedetomidine pro­vides an effective level of sedation for ambulant ophthalmic surgery and maintaining patient­surgeon contact.
  2. Safety is confirmed by a low level of critical incidents, no respiratory depression at the target sedation level.
  3. The patency of the upper airways was better compared to previous experience with propofol.

Downloads

Download data is not yet available.

References

Guryanov VA. Modern multicomponent balanced anesthesia: optimization of the assessment of the operational and anesthetic risk, preoperative preparation and the component of analgesia. (Dis. Doctor of Medical Sciences). Moscow Medical Academy named after I.M.Sechenov. Moscow; 2003.

Duka IG. The use of Dexmedetomidine hydrochloride for procedural sedation. Hirurgiya oglyad. 2019; from 20-21.

Kovalev MG, Shlyk IV, Polushin YUS, Akopov AL, Smirnov AA, Rusanov AA. Experience of using dexmedetomidine for drug sedation in intraluminal endoscopic interventions. Bulletin of Anesthesiology and Reanimatology. 2016; 13 (6).

Annex summary of product characteristics dexdor. [internet]. Available from: https://ec.europa.eu/health/documents/community-register/2017/20171208139366/anx_139366_en.pdf

O'Daniel TG, Shanahan PT. Dexmedetomidine: A new α-agonist anesthetic agent for facial rejuvenation surgery. Aesthetic surgery journal. 2006 Jan 1;26(1):35-40.

Taghinia AH, Shapiro FE, Slavin SA. Dexmedetomidine in Aesthetic Facial Surgery: Improving Anesthetic Safety and Efficacy. Plastic and Reconstructive Surgery [Internet]. Ovid Technologies (Wolters Kluwer Health); 2008 Jan;121(1):269–76. Available from: https://doi.org/10.1097/01.prs.0000293867.05857.90

Shapiro FE. Anesthesia for outpatient cosmetic surgery. Current Opinion in Anaesthesiology [Internet]. Ovid Technologies (Wolters Kluwer Health); 2008 Dec;21(6):704–10. Available from: https://doi.org/10.1097/aco.0b013e328318694f

Nasreen F, Bano S, Khan RM, Hasan SA. Dexmedetomidine used to provide hypotensive anesthesia during middle ear surgery. Indian Journal of Otolaryngology and Head & Neck Surgery [Internet]. Springer Science and Business Media LLC; 2009 Sep;61(3):205–7. Available from: https://doi.org/10.1007/s12070-009-0067-8

Volkov PA, Guryanov VA. VARIED ANESTHESIA DEPENDING ON AUTONOMIC TONE DURING LAPAROSCOPIC SURGERY. Annals of critical care [Internet]. Practical Medicine Publishing House; 2017;(2):26–30. Available from: https://doi.org/10.21320/1818-474x-2017-2-26-30

Досвід застосування Дексмедетомідину для інтраопераційної анальгоседації при проведенні офтальмологічних операцій

Published

2021-11-15

How to Cite

1.
Khodakovsky M. Experience of Dexmedetomidine using for intraoperative analgosedation during ophthalmic operations. PMJUA [Internet]. 2021 Nov. 15 [cited 2021 Dec. 8];6(3):36-41. Available from: https://painmedicine.org.ua/index.php/pnmdcn/article/view/270

Issue

Section

Original article